Fibro-sclerotica nella prostata

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Download PDF. Fibro-sclerotica nella prostata 19, - Francesco Antonaccio Italy. Journal of Plastic Dermatology ; 5,2: 1 Zelickson BD. Il fibro-sclerotica nella prostata che vive e opera sul territorio e svolge la sua professione liberamente o negli ambulatori pubblici si confronta quotidianamente con le problematiche più frequenti e deve cercare di offrire soluzioni valide e rapide.

Negli ultimi anni il dermatologo non è più solo un prescrittore di pomate ma utilizza sempre più strumenti di alta tecnologia sia per la diagnostica che per le terapie: dermatoscopi, ecografi, microscopi confocali, laser, radiofrequenza, ecc. La figura del vecchio dermatologo a cui bastava solo una lente di ingrandimento e una penna per scrivere sta velocemente cambiando. Il giovane dermatologo ha capiDermatology will have a great future if we are able to understand the needs and to che il suo compito non si limita a expectations of our patients in time.

Dermatologists who work in the field, be it as curare la pelle malata fibro-sclerotica nella prostata anche quando private practitioners or in public hospitals, confront the more frequent problems on essa è sana, per mantenerla sana e gioa daily basis and must constantly strive to offer valid and rapid solutions.

In the last vane il più a lungo possibile. Per capire few years, the dermatologist has become fibro-sclerotica nella prostata than just fibro-sclerotica nella prostata prescriber of creams. Fibro-sclerotica nella prostata instruments include dermatoscopes, echographs, confocal microscopes, abbiamo chiesto di rispondere via web lasers, and radio frequencies e. The traditional image of the fibro-sclerotica nella prostata, for whom a magnifying glass and a pen Sono stati evidenziati importanti dati for writing were sufficient, is rapidly changing.

The fibro-sclerotica nella prostata dermatologist has clearstatistici che rappresentano una prima ly understood that his job is not limited to treating ill skin. You will find all the results potranno trovare tutti i risultati di queof this fibro-sclerotica nella prostata interesting survey inside this volume of JPD. Tribunale di Milano n. Via Bassini, 41 - Milano Tel. Via Bassini, 41 - Milano Journal of Plastic Dermatology ; 6, 1 3 Topical photodynamic therapy for the treatment of mild to moderate acne: results of a multicenter, prospective, month follow up study Pietro Cappugi 1,2 Claudio Comacchi Giovanni Menchini 1,2 Pier Luca Bencini 3,4 Michela Gianna Galimberti 3,4 Matteo Tretti Clementoni fibro-sclerotica nella prostata Daniele Torchia 2 Summary Topical photodynamic therapy for the treatment of fibro-sclerotica nella prostata to moderate acne: results of a multicenter, prospective, month follow up study Photodynamic therapy PDT has been attempted for a wide range of dermatologic entities other than the commonly utilized indications of actinic keratoses, basal cell carcinoma and squamous cell carcinoma.

Recent data suggest that fibro-sclerotica nella prostata treatments, including visible light, specific narrowband light, intense pulsed light, pulsed dye laser, and PDT with or without photosensitizing agents, are useful in acne and offer greatest utility when used as an adjunct to medical therapy or for patients who refuse or cannot tolerate medical therapy.

The purpose of this study was to evaluate the efficacy and tolerability of topical PDT in the treatment of acne.

PDT treatment can lead to the eradication of etiological bacteria to acne and the suppression of new papulopustular lesions for about 24 months. Recent data suggest that light-based treatments, including visible light, specific narrowband light, fibro-sclerotica nella prostata pulsed light, pulsed dye laser, and photodynamic therapy PDT with or without photosensitizing agents, are useful in acne and offer greatest utility when used as an adjunct to medical therapy or for patients who refuse or cannot tolerate medical therapy PDT using 5-aminolevulinic acid ALA or methylaminolevulinate MAL is a safe and effecti- ve option for the treatment of several premalignant, malignant and noncancerous skin disorders, including acne.

After topical application, ALA and MAL are taken up mainly by cells of epithelial origin and are converted by haem biosynthesis into photosensitizing porphyrins, mainly protoporphyrin IX. Following activation to the photosensitizer with light of the appropriate wavelength nmreactive oxygen species, in particular singlet oxygen, are generated and finally lead to cell death via necrosis fibro-sclerotica nella prostata apoptosis 5, 6.

Although demonstrated mainly in vitro, at least two mechanisms are thought to be important in acne: 1 destruction of Propionibacterium acnes, which normally produces porphyrins that absorb visible light at wavelengths between and nm; 2 damage of sebaceous gland cells with subsequent reduction of sebum excretion for prolonged periods of time 1, 4, A number of clinical trials have demonstrated the effectiveness and safety fibro-sclerotica nella prostata PDT in acne Journal of Plastic Dermatology ; 6, 1 5 P.

Cappugi, C. Comacchi, G, Menchini, P. Bencini, M. Galimberti, M. Tretti Clementoni, D. Torchia However, the small sample size of the various series, the frequent lack of appropriate controls, widely differences in study designs fibro-sclerotica nella prostata of acne severity, type of prodrug and light sources, incubation time, number of sessions, outcome measures, short-term follow up have prevented PDT from being rated with a high level of evidence in acne so far 1.

We report herein the results of a study aimed at evaluating the maintenance of clinical results obtained with PDT in patients with mild to moderate acne over a month follow up period. After enrollment, patients were asked to apply a salycilic acid plus glycolic acid cream on the areas to be treated starting from 10 days fibro-sclerotica nella prostata the treatment session. Gender Number After 3 hours, the application sites were irFemales 59 radiated with fibro-sclerotica nella prostata Males 47 of red light with a peak Total emission at nm.

The same procedure was repeated every other fibro-sclerotica nella prostata for 4 times acne stage I or 6 times acne stage II. Follow-up visits were performed 3, 6, fibro-sclerotica nella prostata, 18, and 24 months after the last PDT session. Patients were also fibro-sclerotica nella prostata not to undergo any other pharmacologic or physical treatment for acne till the end of follow-up. Digital pictures were taken before the first treatment session and during each follow-up visit.

Clinical improvement was globally assessed by two independent dermatologists, who graded changes in acne from a small set of fixed-magnification clinical photographs. The percentage of positive responders was than calculated. Fibro-sclerotica nella prostata females affected by polycystic ovary syndrome and 6 fibro-sclerotica nella prostata with acne stage III-IV were excluded. Fifty-nine females age range Table 1. Demographic data of our case series.

Number and percentage of patients with positive results over various follow up visits. Ten females and 6 males fibro-sclerotica nella prostata used topical antibiotics during the previous months.

All patients showed an initial clinical improvement mainly reduction of open comedones and inflammation — many of whom already after the first PDT session — and disappearance of most lesions by the end of the treatment cycle Figures The skin texture also showed an evident improvement. Nonetheless, important differences were detected among several subgroups.

An acne patient with some papulopustular lesions. The view just before the first PDT. Torchia Figure 2. An acne patient with many papulopustular lesions and several large cystic lesions. One year after one PDT series six treatments.

One fibro-sclerotica nella prostata after one PDT series six treatments b a Figure 4. An fibro-sclerotica nella prostata patient with some cystic lesions. The majority of PDT trials for acne reported to date showed a bene- 8 Journal of Plastic Dermatology ; 6, 1 b fit from using PDT compared with light therapy alone 2.

Multiple treatments appeared to be superior to single treatments, especially at longer follow-up periods. The major disadvantage of PDT was that some participants experienced Topical photodynamic therapy for the treatment of mild to moderate acne: results of a multicenter, prospective, month follow up study side-effects pain, erythema, desquamation severe enough for them to discontinue the treatment. However, those trials which looked at patient satisfaction score for PDT showed that most patients felt their acne had improved significantly 2.

A major fibro-sclerotica nella prostata of all studies was a short follow up, ranging from a few weeks to a maximum of 6 months 1. Results were better in females than in males, albeit without reaching statistical significance; this finding may possibly reflect a higher severity of lesions in male individuals, but the lack of quantitative assessment of acne severity prevents from confirming this hypothesis.

On the basis of previous studies and the data presented here, the main advantages of the fibro-sclerotica nella prostata of PDT in acne over pharmacologic treatments include: 1 unlimited number of treatment sessions without risk of tachyphylaxis or onset of bacterial resistance; 2 good safety profile without long-term sequelae; 3 quick improvement and mainteinance of results over time without any need to take daily medications; 4 cosmetic effect on skin texture.

Global Alliance to Improve Outcomes in Acne. New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group. Laser and other light therapies for the treatment of acne vulgaris: systematic review.

Br J Dermatol ; Evidencebased review of lasers, light sources and photodynamic therapy in the treatment of acne vulgaris. J Eur Acad Dermatol Venereol ; Topical ALAphotodynamic therapy for the treatment of acne vulgaris. J Invest Dermatol ; Comacchi C, Cappugi P. Terapia Fotodinamica in Dermatologia. Un fibro-sclerotica nella prostata non invasivo di patologie cutanee tumorali e non. Journal of Plastic Dermatology ; 5, Mechanism of action of topical aminolevulinic acid.

In: Photodynamic Therapy. Goldman MP ed.